Global Hyperphosphatemia Drugs Market to Reach US$5.6 Billion by 2030

The global market for Hyperphosphatemia Drugs estimated at US$4.2 Billion in the year 2024, is expected to reach US$5.6 Billion by 2030, growing at a CAGR of 4.9% over the analysis period 2024-2030. Sevelamer, one of the segments analyzed in the report, is expected to record a 4.2% CAGR and reach US$2.2 Billion by the end of the analysis period. Growth in the Calcium-based Phosphate Binders segment is estimated at 5.6% CAGR over the analysis period.

The U.S. Market is Estimated at US$1.1 Billion While China is Forecast to Grow at 7.9% CAGR

The Hyperphosphatemia Drugs market in the U.S. is estimated at US$1.1 Billion in the year 2024. China, the world`s second largest economy, is forecast to reach a projected market size of US$1.2 Billion by the year 2030 trailing a CAGR of 7.9% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 1.9% and 5.1% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 2.9% CAGR.

Key Trends and Drivers

Hyperphosphatemia, characterized by abnormally high phosphate levels in the blood, typically occurs in patients with chronic kidney disease (CKD) or those on dialysis. Managing phosphate levels is crucial as hyperphosphatemia can lead to serious conditions like cardiovascular disease and bone disorders. The primary treatment involves the use of phosphate binders—drugs that bind phosphate in the digestive tract to prevent its absorption. These binders include calcium-based compounds, such as calcium carbonate and calcium acetate, and non-calcium-based agents like sevelamer and lanthanum carbonate, which are preferred due to their lower risk of causing hypercalcemia. The choice of binder often depends on the patient`s overall health, phosphate levels, and existing treatment regimen.

In addition to phosphate binders, dietary management is an integral part of controlling phosphorus levels. However, with the limitations of diet alone to maintain safe phosphorus levels in advanced CKD or dialysis patients, there is a continuous demand for more effective and convenient therapeutic options. Recent advances focus on new formulations and combinations of existing phosphate binders, improving patient adherence and minimizing side effects. There is also growing interest in developing drugs that target the hormonal regulation of phosphate metabolism, offering potential new mechanisms of action beyond binding dietary phosphate.

The growth in the hyperphosphatemia drugs market is driven by several factors, including the increasing prevalence of chronic kidney disease globally, due in part to rising rates of diabetes and hypertension. Advances in dialysis treatment increasing the longevity of CKD patients also contribute to a growing patient population requiring long-term management of phosphate levels. Furthermore, the development of new and more effective phosphate binders and the increasing awareness of the complications associated with hyperphosphatemia stimulate demand for these drugs. Market expansion is also supported by healthcare policies improving access to treatment and the growing focus on enhancing the quality of life for patients with chronic conditions.