Whole Exome Sequencing

A Global Strategic Business Report

MCP15631

RESEARCH DASHBOARD

OCT 2025

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HIGHLIGHTS & REPORT INDEX

Global Whole Exome Sequencing Market to Reach US$7.4 Billion by 2030

The global market for Whole Exome Sequencing estimated at US$2.4 Billion in the year 2024, is expected to reach US$7.4 Billion by 2030, growing at a CAGR of 20.2% over the analysis period 2024-2030. Systems, one of the segments analyzed in the report, is expected to record a 21.3% CAGR and reach US$4.1 Billion by the end of the analysis period. Growth in the Kits segment is estimated at 18.3% CAGR over the analysis period.

The U.S. Market is Estimated at US$677.3 Million While China is Forecast to Grow at 18.8% CAGR

The Whole Exome Sequencing market in the U.S. is estimated at US$677.3 Million in the year 2024. China, the world`s second largest economy, is forecast to reach a projected market size of US$1.1 Billion by the year 2030 trailing a CAGR of 18.8% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 18.5% and 17.1% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 14.3% CAGR.

Global Whole Exome Sequencing Market - Key Trends & Drivers Summarized

What Is Driving the Adoption of Whole Exome Sequencing in Genomic Research?

Whole exome sequencing (WES) is rapidly gaining importance in genomic research and clinical diagnostics due to its ability to provide comprehensive insights into the protein-coding regions of the genome, known as exomes. This method enables researchers to identify genetic variants associated with diseases, including rare genetic disorders, cancers, and neurological conditions, making it a powerful tool for precision medicine. The increasing focus on personalized medicine and the rising prevalence of genetic diseases are driving the adoption of WES in clinical and research settings. Compared to whole-genome sequencing, WES offers a cost-effective approach to studying the exome, providing significant advantages in understanding the genetic basis of diseases and developing targeted therapies.

How Are Technological Advancements Enhancing Whole Exome Sequencing?

Technological advancements in next-generation sequencing (NGS) and bioinformatics are significantly enhancing the efficiency, accuracy, and cost-effectiveness of whole exome sequencing. The development of high-throughput sequencing platforms, improved target enrichment techniques, and optimized library preparation methods are enabling faster and more accurate sequencing of the exome. Innovations in bioinformatics tools and software are improving data analysis and interpretation, allowing researchers to identify clinically relevant genetic variants with greater precision. Additionally, the integration of artificial intelligence (AI) and machine learning (ML) in genomic data analysis is enabling the prediction of disease risk, treatment response, and patient outcomes, further expanding the application of WES in clinical diagnostics and precision medicine.

What Are the Challenges and Opportunities in the Whole Exome Sequencing Market?

The whole exome sequencing market faces several challenges, including the high cost of sequencing, the need for specialized bioinformatics expertise, and ethical concerns related to genetic data privacy. Additionally, the interpretation of genetic variants remains a significant challenge, as many detected variants may have uncertain or unknown clinical significance. However, these challenges also present opportunities for growth and innovation. The development of more cost-effective and scalable sequencing platforms, along with user-friendly bioinformatics tools, can help lower the barriers to adoption and expand the use of WES in clinical practice. The increasing emphasis on rare disease research, cancer genomics, and personalized medicine is creating new growth opportunities for WES as a critical tool for identifying actionable genetic variants. Moreover, the rise of collaborative research networks and genomic databases is driving the need for robust and interoperable sequencing solutions that can integrate with existing healthcare and research infrastructures.

What Is Driving the Growth of the Whole Exome Sequencing Market?

The growth in the Whole Exome Sequencing market is driven by several factors, including the increasing focus on personalized medicine, rising prevalence of genetic disorders, and technological advancements in next-generation sequencing and bioinformatics. The need for comprehensive genomic insights to identify disease-causing variants and develop targeted therapies is significantly boosting market demand for WES in clinical and research settings. Technological innovations in high-throughput sequencing, target enrichment, and AI-driven data analysis are enhancing the efficiency, accuracy, and cost-effectiveness of WES, making it more accessible to a broader range of healthcare providers and researchers. The expansion of precision medicine initiatives, coupled with the growing emphasis on rare disease research and oncology, is also driving market growth as stakeholders seek powerful genomic tools for disease diagnosis, risk assessment, and therapeutic development.

SCOPE OF STUDY

The report analyzes the Whole Exome Sequencing market by the following Segments, and Geographic Regions/Countries:

Segments:

Offering (Systems, Kits, Services); Application (Diagnostics, Drug Discovery & Development, Personalized Medicine, Other Applications).

Geographic Regions/Countries:

World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; and Rest of Europe); Asia-Pacific; Rest of World..

SELECT PLAYERS

Agilent Technologies, Inc.; Ambry Genetics; BGI Europe; Eurofins Genomics GmbH; GENEWIZ, Inc.; Illumina, Inc.; Macrogen, Inc.; Roche Nimblegen, Inc.; Sengenics; Thermo Fisher Scientific, Inc.

AI INTEGRATIONS

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TARIFF IMPACT FACTOR

Our new release incorporates impact of tariffs on geographical markets as we predict a shift in competitiveness of companies based on HQ country, manufacturing base, exports and imports (finished goods and OEM). This intricate and multifaceted market reality will impact competitors by increasing the Cost of Goods Sold (COGS), reducing profitability, reconfiguring supply chains, amongst other micro and macro market dynamics.

I. METHODOLOGY

II. EXECUTIVE SUMMARY

1. MARKET OVERVIEW

Trade Shocks, Uncertainty, and the Structural Rewiring of the Global Economy

How Trump’s Tariffs Impact the Market? The Big Question on Everyone’s Mind

Whole Exome Sequencing – Global Key Competitors Percentage Market Share in 2024 (E)

Competitive Market Presence - Strong/Active/Niche/Trivial for 42 Players Worldwide in 2024 (E)

2. FOCUS ON SELECT PLAYERS

3. MARKET TRENDS & DRIVERS

Advances in Genetic Research Propel the Use of Whole Exome Sequencing

Rising Prevalence of Genetic Disorders Amplifies Demand for Whole Exome Sequencing

Cost Reduction in Sequencing Technologies Spurs Whole Exome Sequencing Adoption

Clinical Applications in Personalized Medicine Enhance Whole Exome Sequencing Capabilities

Pharmaceutical Companies Increasing Investment in Drug Discovery Supports Market Growth

Consumer Interest in Ancestry and Genealogy Expands Market Reach

Expansion of Newborn Screening Programs Drives Whole Exome Sequencing Services

Research and Development in Rare Diseases Bolster Use of Exome Sequencing

Growing Biobanking Activities Sustain Demand for Whole Exome Sequencing

Integration of AI and Machine Learning in Genomic Research Transforms Market Landscape

4. GLOBAL MARKET PERSPECTIVE

World Whole Exome Sequencing Market Analysis of Annual Sales in US$ Thousand for Years 2015 through 2030

World Recent Past, Current & Future Analysis for Whole Exome Sequencing by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Whole Exome Sequencing by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Systems by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Systems by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Kits by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Kits by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Services by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Services by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Diagnostics by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Diagnostics by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Drug Discovery & Development by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Drug Discovery & Development by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Personalized Medicine by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Personalized Medicine by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

World Recent Past, Current & Future Analysis for Other Applications by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

World 6-Year Perspective for Other Applications by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2025 & 2030

III. MARKET ANALYSIS

UNITED STATES

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2025 (E)

USA Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

USA 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

USA Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

USA 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

CANADA

Canada Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Canada 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Canada Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Canada 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

JAPAN

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2025 (E)

Japan Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Japan 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Japan Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Japan 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

CHINA

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2025 (E)

China Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

China 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

China Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

China 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

EUROPE

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2025 (E)

Europe Recent Past, Current & Future Analysis for Whole Exome Sequencing by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2024 through 2030 and % CAGR

Europe 6-Year Perspective for Whole Exome Sequencing by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2025 & 2030

Europe Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Europe 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Europe Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Europe 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

FRANCE

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2025 (E)

France Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

France 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

France Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

France 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

GERMANY

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2025 (E)

Germany Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Germany 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Germany Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Germany 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

ITALY

Italy Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Italy 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Italy Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Italy 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

UNITED KINGDOM

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2025 (E)

UK Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

UK 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

UK Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

UK 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

REST OF EUROPE

Rest of Europe Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Rest of Europe 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Rest of Europe Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Rest of Europe 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

ASIA-PACIFIC

Whole Exome Sequencing Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2025 (E)

Asia-Pacific Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Asia-Pacific 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Asia-Pacific Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Asia-Pacific 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

REST OF WORLD

Rest of World Recent Past, Current & Future Analysis for Whole Exome Sequencing by Offering - Systems, Kits and Services - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Rest of World 6-Year Perspective for Whole Exome Sequencing by Offering - Percentage Breakdown of Value Sales for Systems, Kits and Services for the Years 2025 & 2030

Rest of World Recent Past, Current & Future Analysis for Whole Exome Sequencing by Application - Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications - Independent Analysis of Annual Sales in US$ Thousand for the Years 2024 through 2030 and % CAGR

Rest of World 6-Year Perspective for Whole Exome Sequencing by Application - Percentage Breakdown of Value Sales for Diagnostics, Drug Discovery & Development, Personalized Medicine and Other Applications for the Years 2025 & 2030

COMPETITIVE METRICS

COMPETITORS (ALPHABETICAL)	% VALIDATED RESEARCH *
Agilent Technologies, Inc.	%
CeGaT GmbH	%
Centogene AG	%
GENEWIZ	%
Illumina, Inc.	%
OHMX.bio	%
PreventionGenetics	%
Thermo Fisher Scientific, Inc.	%

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